Addressing Underlying Health Conditions

Other > premature ejaculation treatment


Oral medications: Some men respond well to low doses of the antidepressants known as selective serotonin reuptake inhibitors (SSRIs), that block serotonin, one of the hormones important in ejaculation.

Drug Name Type Common Dosage Side Effects Interaction Notes
Dapoxetine SSRI 30-60 mg daily Nausea, dizziness, headache Taken 1-3 hours before sex
Paroxetine SSRI 20-40 mg daily Fatigue, dry mouth Not approved specifically for PE
Clomipramine Tricyclic antidepressant 25-50 mg daily Drowsiness, weight gain Off-label use

These are prescribed off-label, with some side effects. These pills have been around for over 20 years, are relatively safe, but are not FDA approved for PE / RE.

Symptoms of premature ejaculation

Premature ejaculation cannot always be cured, but it can be treated. Lifelong PE is not usually curable, whereas acquired PE, which often occurs later in life, may be cured by addressing the underlying cause, such as stress, lifestyle, or relationship issues. Most men last between 5 and 7 minutes in bed. That is the time to reach orgasm and ejaculate. However, this can vary from individual to individual.

Cite this article

If you are regularly ejaculating in less than 1 minute, this could indicate premature ejaculation. Viagra is not licensed for premature ejaculation, but some research suggests that PDE-5 inhibitors can improve confidence, sexual satisfaction, and ejaculatory control. No, masturbation does not cause premature ejaculation. Controlled masturbation techniques can help you manage premature ejaculation. PE is usually caused by underlying factors, like stress, anxiety, or depression.

Treating delayed ejaculation

Yes, Kegel exercises can help manage premature ejaculation. Research shows that 82.5% of people who completed a 12-week pelvic floor exercise program increased their time to ejaculation from less than 60 seconds to 146 seconds. Yes, some STIs can cause premature ejaculation, especially those that cause chronic prostatitis, like chlamydia. If you think you may be affected, you can order an at-home chlamydia test. Yes, lifestyle changes like increasing exercise can help you effectively manage premature ejaculation. It is therefore up to the patient and his doctor to make the call to use this class of drugs off label. Don’t be afraid to seek treatment for premature or rapid ejaculation.

Product Dosage Quantity + Bonus Price
Cialis Professional40mg180 + 4 Pills618.23€ 588.79€
Levitra Generic20mg10 Pills31.49€ 29.99€
Kamagra Gold100 mg20 Pills86.09€ 81.99€
Levitra Generic10mg60 + 6 Pills112.98€ 107.60€
Kamagra Polo100mg12 Pills60.21€ 57.34€
Kamagra Gold100 mg32 Pills121.24€ 115.47€
Kamagra Polo100mg60 + 4 Pills189.39€ 180.37€
Cialis Generic60mg60 + 4 Pills145.06€ 138.15€
Cialis Super Active20mg90 + 10 Pills314.14€ 299.18€
Kamagra Oral Jelly100mg10 Sachets54.55€ 51.95€
Kamagra Oral Jelly100 mg220 + 18 Sachets662.24€ 630.70€
Levitra Generic60mg180 + 10 Pills501.43€ 477.55€
Priligy Generic Dapoxetine60mg30 + 6 Pills106.65€ 101.57€
Viagra Soft Tabs100mg10 Pills36.93€ 35.17€
Kamagra Effervescent Tablets100 mg28 Pills90.83€ 86.50€

It is a very common condition, and one of the most common sexual dysfunctions. Your UCLA Men’s Clinic provider will be understanding and likely have an effective treatment that will please you and your partner.

  • Start therapy early with a healthcare provider.
  • Learn about psychological factors affecting performance.
  • Use behavioral techniques to increase endurance.
  • Consider antidepressants like SSRIs under medical supervision.
  • Explore natural supplements such as L-arginine or herbal remedies.
  • Practice mindfulness and stress reduction strategies.
  • Avoid performance anxiety through relaxation exercises.
  • Maintain a balanced diet to support sexual health.
  • Limit distractions and focus on intimate connection.
  • Track triggers or patterns that lead to early ejaculation.
  • Use lubricants to decrease sensation and prolong intimacy.
  • Seek support from sex education resources.

Board-certified urologists staff The Men’s Clinic at UCLA and you can be assured you are getting an experienced physician performing your evaluation and procedure in a relaxed and comfortable environment.

18. Does Viagra make you last longer before ejaculation?

Treatment for PE and RE centers around behavioral, neurologic and hormonal modifications. Behavioral Therapy: Some patients respond to techniques such as starting and stopping. This basically involves interrupting intercourse to decrease stimulation to the penis in hopes of cooling the nerves down. Although effective at times, most patients report limited sexual satisfaction with these methods. Topical medications: One of the simplest treatment option is to temporarily desensitize the head of the penis by using a topical anesthetic medications for premature ejaculation.

Information to gather in advance

They are effective, easy-to-use, low-cost and have a negligible risk of systemic side effects. Topical numbing sprays and creams are available with either a prescription or over the counter. They all work by gently numbing the sensitive areas of the penis so the nerves don’t fire so fast and the man can prolong intercourse. The agent must be washed off prior to intercourse or a condom must be worn to make sure the partner is not also desensitized. One option for patients is a new product, Promescent®, from Absorption Pharmaceuticals, which provides improved ejaculatory latency (the time from penetration to ejaculation) with minimal loss of sexual sensation. For more information and to schedule an appointment, please call the UCLA Urology Appointment line at 310-794-7700. Premature ejaculation (PE)1 is the most common type of sexual dysfunction in men. It affects as many as 30% to 40% of all men at some point in their life.

Supplement / Remedy Possible Benefit Notes
Ginseng May improve sexual stamina Consult physician before use
Zinc Supplements Supports testosterone levels Dosage as per guidelines
Ashwagandha Reduces stress, enhances stamina Not scientifically conclusive
Kegel Exercises Strengthen pelvic floor muscles Daily routine

It can have a wide range of causes, from hypersensitivity to medical conditions to psychological factors.The critical thing to remember when treating PE is that you are not alone. The condition is very common, even if it is not openly discussed, and is easily treatable. Premature ejaculation (PE) treatments include prescription pills, numbing creams and desensitizing wipes. Each works differently to help delay climax.

Other Therapy

One study found that yoga, running, and high-intensity interval training (HIIT) could effectively manage premature ejaculation similarly to medication. British Society for Sexual Medicine (BSSM) Position Statement on Premature Ejaculation, The World Journal of Men’s Health [accessed 10 September 2025] Chlamydia trachomatis infection is related to premature ejaculation in chronic prostatitis patients: results from a cross-sectional study, The Journal of Sexual Medicine [accessed 10 September 2025] Effects of physical exercise interventions on ejaculation control, Sexual Medicine Reviews [accessed 10 September 2025] (284) EFFICACY OF PELVIC FLOOR MUSCLE TRAINING AND KEGEL EXERCISES IN THE TREATMENT OF PREMATURE EJACULATION: AN INTEGRATIVE LITERATURE REVIEW, The Journal of Sexual Medicine [accessed 10 September 2025] Ejaculation problems, NHS [accessed 10 September 2025] EMLA Cream 5% (5g pack), emc [accessed 10 September 2025] Medical therapy for premature ejaculation, Therapeutic Advances in Urology [accessed 10 September 2025] Premature ejaculation, NICE [accessed 10 September 2025] Premature Ejaculation, NIH [accessed 10 September 2025] Priligy 30 mg film-coated tablets, emc [accessed 10 September 2025] We provide men’s health care in one convenient clinic. To learn more about our services, call 310-794-7700. It can be either primary, meaning the man has always had the problem, or secondary, meaning the man has acquired the condition later in life. Premature ejaculation has various timing definitions ranging from ejaculating within one minute of penetration to ejaculating prior to a man's partner achieving orgasm.

Medical treatments

Essentially, a man or a couple can suffer from rapid ejaculation if one or both is unhappy with how rapidly the man ejaculates. For some couples, RE can occur 30 seconds into vaginal penetration. For others, RE may extend out to five or ten minutes. As long as one of the partners is dissatisfied, RE is a problem. A man doesn’t have much control over how quickly he ejaculates.

Start-and-stop and squeeze methods

Ejaculation is mostly an event of the autonomic nervous system, the part of our nervous system we can’t fully control. Heartbeat, digestion, sweating are all examples of neurologic processes our autonomic nervous system controls. Therefore, when a man gets a signal to ejaculate, the point of no return, he’s going to go. The most sensitive part of the penis is the area around the frenulum, the skin flap on the underside of the penis just below the urethral meatus (where he urinates). There is a spinal cord pathway that connects there and rapidly sends signals to the ejaculation center of the spinal cord. Numbing creams and wipes contain local anesthetics such as lidocaine, which reduce sensation on the skin. Prescription pills – like SRIs (sertraline, paroxetine) and PDE5 inhibitors (sildenafil, tadalafil, vardenafil) – are often also used to treat PE by adjusting serotonin levels in the brain, which can help prolong intimacy.

  • Recognize signs of performance anxiety and address them.
  • Use distraction techniques to divert focus from orgasm.
  • Combine treatments like behavioral therapy and medication.
  • Limit caffeine intake which can increase arousal.
  • Practice deep, slow breathing to relax before sex.
  • Consider topical anesthetics to desensitize.
  • Use distraction and timing techniques to improve control.
  • Educate yourself about normal sexual response.
  • Attend couple's therapy to improve communication.
  • Keep a positive attitude and avoid shame.
  • Explore different positions to find what prolongs pleasure.
  • Stay committed to a treatment plan for the best results.

The best PE treatment depends on your symptoms, preferences and any other health concerns.

5. Is premature ejaculation treatable?

Serotonin, dopamine, prolactin, testosterone and oxytocin are all hormones that play a role in ejaculation. This is a very troubling condition for men as it compromises their sexual satisfaction and inhibits them in relationships. Some recent studies shed light on PE and RE but the exact causes are still not known. Psychological: Classic literature on RE suggests it is a trained sexual response fostered by men secretively masturbating as adolescents and trained to finish quickly. This behavior was then reinforced with early partner encounters where young couples engage in clandestine sexual activity in parents’ basements or car back seats.

Prevalence of premature ejaculation in India

There is no proof that this is a real buy tadalista 60 thing, however, and physicians suggesting this as a cause of RE reinforces guilt associations with sexuality. Neurobiological: The neurotransmitter serotonin (5HT) plays a central role in the ejaculatory response. Low levels of serotonin in specific areas of the brain may lead premature ejaculation. Studies have shown that increases in serotonin levels can help delay ejaculation in some men. This provides the rationale for treating RE with anti-depressants in the selective serotonin reuptake inhibitor (SSRI) class.

Acquired premature ejaculation

Penile Sensitivity: The ejaculatory spinal cord pathway is located at the ventral tip of the corona (if you’re standing up and looking down at your penis, the ventral side is on the bottom. The corona is the mushroom head of your penis.) If a man has increased sensitivity at that point, he will likely ejaculate too fast. Applying topical numbing agents, usually containing lidocaine, is an effective way to reduce penile sensitivity and prolong ejaculation. It is important to wash the penis prior to intercourse, or wear a condom, to avoid desensitizing the partner, however. At UCLA Health—The Men’s Clinic, physicians are trained to treat rapid ejaculation and have a number of methods available. A licensed provider can help you choose the right option for safe and effective results. Premature ejaculation treatments are available in two main types: topical and oral medications. Topical treatments are applied directly to the genitals to reduce sensation and help delay ejaculation. Common options include desensitizing creams or sprays and benzocaine wipes. Oral medications can help men maintain an erection or delay climax.

  • Consider professional counseling for psychological causes.
  • Use behavioral exercises like stop-start method.
  • Take prescribed SSRIs to delay ejaculation.
  • Practice pelvic floor relaxation techniques.
  • Maintain a healthy, balanced diet.
  • Limit exposure to performance pressure.
  • Engage in shared sexual experiences with partner.
  • Use condoms with numbing agents if suitable.
  • Track progress to stay motivated.
  • Incorporate relaxation techniques before intimacy.
  • Avoid rushing; focus on quality over speed.
  • Seek group or couple therapy if needed.

Two main categories used for premature ejaculation are selective serotonin reuptake inhibitors (SSRIs), which are a type of antidepressant, and PDE5 inhibitors, which are typically prescribed for erectile dysfunction. Topical treatments are applied directly to the genitals anywhere from five to 20 minutes before intercourse to reduce sensation and have been shown to delay orgasm in men by three to six minutes.2 However, for some users, topical treatments can cause loss of sexual desire or erectile disruption due to numbness.3 One risk of using topical treatments for PE is that the numbing ingredients can transfer to your partner, reducing sensation for them as well.