5 WARNINGS AND PRECAUTIONS
Use with strong CYP3A inhibitors: Not recommended.
| Parameter | Details |
|---|---|
| Onset of Action | 30-60 minutes |
| Peak Effect | About 1 hour |
| Duration of Effect | 4-6 hours |
| Factors Influencing | Food intake, alcohol, metabolism |
Concomitant PDE-5 inhibitors: Avoid use with Viagra ®or other PDE-5 inhibitors.
- Safe use of sildenafil requires assessment of heart conditions.
- It may cause temporary visual disturbances like blurred vision.
- Do not drive or operate machinery until effects are known.
- Use with caution if you have high or low blood pressure.
- Discuss any other medications with your healthcare provider.
See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.
- Using sildenafil will not cause an erection without sexual stimulation.
- The medication's effectiveness varies among individuals.
- It can be used in men with diabetes-related erectile issues.
- Combining sildenafil with recreational drugs can be dangerous.
- Always consult healthcare providers for personalized advice.
Table of Contents FULL PRESCRIBING INFORMATION: CONTENTS*1 INDICATIONS AND USAGE2 DOSAGE AND ADMINISTRATION2.1 Recommended Dosage in Adults3 DOSAGE FORMS AND STRENGTHS4 CONTRAINDICATIONS5 WARNINGS AND PRECAUTIONS5.1 Hypotension5.2 Worsening Pulmonary
Brand names
Lie down if you feel faint or dizzy. More shortness of breath than usual may be due to your underlying medical condition. decreased eyesight or loss of sight in one or both eyes (NAION). If you notice a sudden decrease or loss of eyesight, talk to your doctor right away. It is not possible to determine whether these events are related directly to this class of oral medicines, including sildenafil tablets, or to other diseases or medicines, to other factors, or to a combination of factors.
What should I do if I miss a dose of sildenafil?
heart attack, stroke, irregular heartbeats, and death. Most of these happened in men who already had heart problems. If it is not treated right away, priapism can permanently damage your penis. The most common side effects with sildenafil tablets include: Nosebleed, headache, upset stomach, getting red or hot in the face (flushing), trouble sleeping, as well as fever, erection increased, respiratory infection, nausea, vomiting, bronchitis, pharyngitis, runny nose, and pneumonia in children. Tell sildenafil citrate 100mg tablets your doctor if you have any side effect that bothers you or doesn’t go away.
Allergy warning
These are not all the possible side effects of sildenafil tablets. For more information, ask your doctor or pharmacist. You may report side effects to FDA at 1-800-FDA-1088. Store sildenafil tablets at controlled room temperature, between 20°C to 25°C (68°F to 77°F). Keep sildenafil tablets and all medicines away from children. Vascular Occlusive Disease5.3 Epistaxis5.4 Visual Loss5.5 Hearing Loss5.6 Combination with other PDE-5 Inhibitors5.7 Priapism5.8 Vaso-occlusive Crisis in Patients with Pulmonary Hypertension Secondary to Sickle Cell Disease6 ADVERSE REACTIONS6.1
| Use Case | Description | Typical Dosage | Notes |
|---|---|---|---|
| Treatment of Erectile Dysfunction | Improves blood flow to the penis | 20 mg as needed | Taken 30-60 minutes before sexual activity |
| Pulmonary Hypertension | To reduce blood pressure in lungs | 20 mg thrice daily | Prescribed by doctor |
| Off-label Uses | Potential treatment for other conditions | Varies | Under medical supervision |
Clinical Trials Experience6.2 Post-marketing Experience7 DRUG INTERACTIONS8 USE IN SPECIFIC POPULATIONS8.1 Pregnancy8.2 Lactation8.4 Pediatric Use8.5 Geriatric Use8.6 Patients with Hepatic Impairment8.7 Patients with Renal Impairment10 OVERDOSAGE11 DESCRIPTION12 CLINICAL
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 200mg | 360 + 10 Pills | 481.98€ 459.03€ | |
| Viagra Generic | 150mg | 120 + 8 Pills | 177.58€ 169.12€ | |
| Viagra Generic | 150mg | 360 + 10 Pills | 423.48€ 403.31€ | |
| Kamagra Soft Tabs | 100mg | 84 + 4 Pills | 233.05€ 221.95€ | |
| Viagra Generic | 200mg | 180 + 10 Pills | 277.56€ 264.34€ | |
| Viagra Generic | 50mg | 270 + 8 Pills | 198.48€ 189.03€ | |
| Viagra Generic | 25mg | 30 + 4 Pills | 47.97€ 45.69€ | |
| Viagra Generic | 150mg | 180 + 10 Pills | 236.46€ 225.20€ | |
| Viagra Generic | 100mg | 10 Pills | 28.91€ 27.53€ | |
| Kamagra Polo | 100mg | 20 Pills | 83.56€ 79.58€ | |
| Kamagra | 100mg | 60 + 4 Pills | 201.34€ 191.75€ | |
| Viagra Generic | 25mg | 90 + 6 Pills | 105.03€ 100.03€ |
PHARMACOLOGY12.1 Mechanism of Action12.2 Pharmacodynamics12.3 Pharmacokinetics13 NONCLINICAL TOXICOLOGY13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility14 CLINICAL STUDIES17 PATIENT COUNSELING INFORMATION*Sections or subsections omitted from the full prescribing information are not listed.
What should I know about storage and disposal of this medication?
See “What are the ingredients in sildenafil tablets?” at the end of this leaflet. What should I tell my doctor before taking sildenafil tablets? Tell your doctor about all of your medical conditions, including if you have heart problems such as angina (chest pain), heart failure, irregular heartbeats, or have had a heart attack have a disease called pulmonary veno-occlusive disease (PVOD) have high or low blood pressure or blood circulation problems have an eye problem called retinitis pigmentosa have or had loss of sight in one or both eyes have any problem with the shape of your penis or Peyronie’s disease have any blood cell problems such as sickle cell anemia have a stomach ulcer or any bleeding problems are pregnant or planning to become pregnant. It is not known if sildenafil tablets could harm your unborn baby. It is not known if sildenafil citrate passes into your breast milk or if it could harm your baby.
What should I tell my healthcare provider before taking sildenafil?
Tell your doctor about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal products. The doses of some of your medicines may need to be adjusted while you take sildenafil tablets. Especially tell your doctor if you take See “What is the most important information I should know about sildenafil tablets?” See “What is the most important information I should know about sildenafil tablets?” Ritonavir (Norvir ®) or other medicines used to treat HIV infection Keep a list of your medicines and show it to your doctor and pharmacist when you get a new medicine. Take sildenafil tablets exactly as your doctor tells you. Sildenafil citrate may be prescribed to you as Take sildenafil tablets 3 times a day about 4 to 6 hours apart.
What should I do if I accidentally use too much sildenafil?
Take sildenafil tablets at the same times every day. If it is close to your next dose, skip the missed dose, and take your next dose at the regular time. Do not change your dose or stop taking sildenafil tablets on your own. If you take too much sildenafil tablets, call your doctor or go to the nearest hospital emergency room. What are the possible side effects of sildenafil tablets? 1 INDICATIONS AND USAGE AdultsSildenafil tablets are indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults
- Sildenafil 20 mg tablets are sometimes used off-label for pulmonary hypertension.
- The medication can cause priapism, a painful, prolonged erection.
- Wait at least 24 hours before taking another dose.
- Avoid grapefruit juice, which can increase drug levels.
- Report any allergic reactions such as rash or difficulty breathing.
to improve exercise ability and delay clinical worsening [see Clinical Studies (14)] .Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) tablets.
Comparing Side Effects
Medicines are sometimes prescribed for purposes that are not in the patient leaflet. This patient leaflet summarizes the most important information about sildenafil tablets. You can ask your doctor or pharmacist for information about sildenafil tablets that is written for health professionals. For more information go to or call 1-855-361-3993. What are the ingredients in sildenafil tablets?
Usual Adult Dose for:
This product’s label may have been updated. For current full prescribing information, please visit This Patient Information has been approved by the U.S. Food and Drug Administration Sildenafil is a vasodilator, which will relax blood vessels and increase blood flow to lungs and other specific organs. To process your order we will require a prescription from you or your Prescriber. We will only compound and dispense upon receipt of a valid patient specific prescription.
More common
Please note that our compounds are exclusively provided for individual patient and are not for office use. Your prescriber can mail or fax in the prescription You can mail in the original prescription We can contact your prescriber for you You can transfer your prescription from another pharmacy We have convenient ways to get your prescription to us: Fax to (800) 786-1405 or (844) 922-7379Send electronically (e-prescribe) by: Searching for CareFirst Specialty Pharmacy in Mount Laurel, NJ 08054Using our NCPDP# 3151266Phone into (844) 822-7379 Fax to (800) 786-1405 or (844) 922-7379 Send electronically (e-prescribe) by: Searching for CareFirst Specialty Pharmacy in Mount Laurel, NJ 08054Using our NCPDP# 3151266 Searching for CareFirst Specialty Pharmacy in Mount Laurel, NJ 08054 For more information about our products and services: Please complete the prescriber form onlineEmail us at [email protected] We are a nationally accredited PCAB compounding pharmacy and a .Pharmacy verified website. A verified .Pharmacy website designation ensures our patients and prescribing partners that our website is verified and safe. Please contact us if your pet needs a custom strength. Troches and suppositories require refrigeration (ice packs) and will incur an extra charge of $19.95 per order. Sildenafil tablets are indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening [see Clinical Studies (14)] .
Usual Pediatric Dose for Pulmonary Hypertension
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use SILDENAFIL TABLETS safely and effectively. See full prescribing information for SILDENAFIL TABLETS.SILDENAFIL tablets, for oral useInitial U.S. Approval: 1998INDICATIONS AND USAGEAdultsSildenafil tablets are a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening. (1)DOSAGE AND ADMINISTRATIONAdults: 20 mg three times a day. (2.1)DOSAGE FORMS AND STRENGTHSTablets: 20 mg (3)CONTRAINDICATIONSWARNINGS AND PRECAUTIONSVasodilation effects may be more common in patients with hypotension or on sildenafil tablets 125 antihypertensive therapy.
Professional resources
(5.1)Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended. (5.2)Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs. (5.4, 5.5)Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil citrate may cause serious vaso-occlusive crises. (5.8)ADVERSE REACTIONSDRUG INTERACTIONSUse with strong CYP3A inhibitors: Not recommended. ( 7, 12.3)Concomitant PDE-5 inhibitors: Avoid use with Viagra ®or other PDE-5 inhibitors.
Sildenafil side effects
(5.6)Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) tablets. However, due to Viatris Specialty LLC’s marketing exclusivity rights, this drug product is not labeled with that information.See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.Revised: 3/2026 Sildenafil tablets are a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening. Adults: 20 mg three times a day. Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended. Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil citrate may cause serious vaso-occlusive crises. 2 DOSAGE AND ADMINISTRATION 2.1 Recommended Dosage in AdultsOral DosageThe recommended dosage of sildenafil tablet is 20 mg three times a day [see Clinical Studies (14)] .Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) tablets.
| Medication Type | Interaction Effect | Risk Level | Recommendation |
|---|---|---|---|
| Nitrates | Severe hypotension | High | Do not combine |
| Alpha-blockers | Increased risk of blood pressure drop | Moderate | Use under medical supervision |
| CYP3A4 inhibitors | Increased sildenafil levels | Moderate | Adjust dose or avoid |
| Ritonavir | Elevated risk of side effects | High | Consult healthcare provider |
The recommended dosage of sildenafil tablet is 20 mg three times a day [see Clinical Studies (14)] .
- Sildenafil 20 mg tablets are manufactured by several pharmaceutical companies.
- Generic versions are usually less expensive than brand-name options.
- The drug works by inhibiting phosphodiesterase type 5 enzyme.
- Patients should report any unusual symptoms promptly.
- It is important to have a proper diagnosis before starting treatment.