What is Hezkue spray? Oral sildenafil spray for erectile dysfunction

Impotence Spray vs. Other ED Treatments
What is Hezkue Spray and How Does It Work?
8. Use In Specific Populations
7. Drug Interactions

Always consult with a health professional for a tailored prescription.

Impotence Spray vs. Other ED Treatments

Study UNICO: perception of urologists and andrologists, in Spain, about the use of sildenafil oral suspension in patients sildenafil syrup with erectile dysfunction. For more information contact Aspargo UK, 2 Cabot House, Compass Point Business Park, St Ives, United Kingdom, PE27 5JL. Legal information, Aspargo Labs Italia S.r.l., Via Po, 102, 00198 Rome – Italy. Reporting forms and information can be found at or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Aspargo Labs by emailing safety@aspargolabs.com or by calling 01480 465755 Reporting forms and information can be found at or search for MHRA Yellow Card in the Google Play or Apple App Store.

Who should not take sildenafil?

Adverse events should also be reported to Aspargo Labs by emailing safety@aspargolabs.com or by calling 01480 465755 During a typical ED consultation for erectile dysfunction treatment, the conversation might go like this: Me: “What did you book this consultation for today?”Man (glancing at his feet): “I think I have erectile dysfunction.”Me: “No worries. This is a common issue—did you know that 1 in 3 men over 45 experience erectile dysfunction? Even younger blokes can face these challenges. What treatments or ED medications have you sildenafil citrates tried so far?”Man: “I tried Viagra, but it didn’t work.”Me: “Did you wait at least an hour after taking it before stimulation? Proper ED medication use is crucial.”Man: “No.”Me: “And did you know that taking sildenafil on an empty stomach makes a big difference? In addition to traditional oral options, the latest innovation in ED treatment is the Spontan nasal spray. Here’s why this alternative could be right for you: Rapid Onset:Intranasal delivery can begin working in as little as 15 minutes—much faster than the typical 30–60 minutes for oral tablets.

Sildenafil spray utilizes absorption through oral mucosa.
It provides a discreet alternative for erectile issues.
Use the spray about 10-20 minutes before intimacy.
It generally has fewer gastrointestinal side effects.
The spray must be kept out of reach of children.
Users should avoid alcohol to prevent adverse reactions.
Compatibility with other medications should be checked.
The spray may be part of a comprehensive ED treatment plan.
Discontinue use and consult a doctor if adverse reactions occur.
The spray’s effectiveness can improve confidence in men.
Training on proper application enhances safety and effectiveness.

Bypassing the Gastrointestinal Tract:Nasal absorption avoids the gastrointestinal tract and first-pass metabolism, leading to a more consistent effect.

Product	Dosage	Quantity + Bonus	Price
Viagra Generic	150mg	360 + 10 Pills	423.48€ 403.31€
Viagra Generic	25mg	90 + 6 Pills	105.03€ 100.03€
Kamagra Soft Tabs	100mg	60 + 4 Pills	180.59€ 171.99€
Kamagra Polo	100mg	12 Pills	60.21€ 57.34€
Viagra Generic	25mg	60 + 4 Pills	71.99€ 68.56€
Viagra Generic	25mg	120 + 6 Pills	125.56€ 119.58€
Kamagra Oral Jelly	100mg	110 + 9 Sachets	334.87€ 318.92€
Viagra Generic	200mg	270 + 10 Pills	379.76€ 361.68€
Kamagra Soft Tabs	100mg	272 + 12 Pills	593.42€ 565.16€
Kamagra Polo	100mg	20 Pills	83.56€ 79.58€
Kamagra	100mg	32 Pills	121.24€ 115.47€
Viagra Generic	100mg	60 + 4 Pills	96.36€ 91.77€
Viagra Generic	25mg	270 + 8 Pills	184.26€ 175.49€
Viagra Generic	200mg	60 + 4 Pills	125.19€ 119.23€
Viagra Generic	200mg	120 + 8 Pills	204.80€ 195.05€
Kamagra	100mg	84 + 6 Pills	264.44€ 251.85€

Fewer Side Effects:Many patients report experiencing fewer side effects with nasal spray formulations compared to oral medications. Enhanced Convenience:Ideal for those who have difficulty swallowing pills or for blokes who seek spontaneity without having to plan around meal times. Remember: As with any ED treatment, proper use and consultation with a health care professional are essential.

What is Hezkue Spray and How Does It Work?

Aspargo receives regulatory approval to market sildenafil spray in Germany, Ireland, and the Netherlands. Conventional treatments for erectile dysfunction (ED) require planning and may cause timing anxiety with delayed onset of action.1 Hezkue®, a sildenafil suspension, is the first phosphodiesterase type 5 (PDE-5) inhibitor suspension spray for ED that offers flexible dose adjustment based on individual patient needs.2 The below is a MIMS summary of the Hezkue® product characteristics. Please refer to the full Summary of Product Characteristics (SPC) before prescribing. INDICATIONAdult men with erectile dysfunction, which is the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance. In order for Hezkue to be effective, sexual stimulation is required.

Can I get Hezkue on the NHS?

DOSAGEAdult: Recommended dose is 50mg (4 actuations) orally approx 1 hr before sexual activity. This may be decreased to 25mg (2 actuations) or increased to 100mg (8 actuations) as needed; max 100mg once daily. CONTRAINDICATIONSHypersensitivity to the active substance or excipients. Cardiac conditions where sexual activity is inadvisable, non-arteritic anterior ischaemic optic neuropathy, severe hepatic impairment, hypotension, recent stroke or MI, hereditary degenerative retinal disorders. WARNINGSCardiovascular disease, left ventricular outflow obstruction, severe autonomic dysfunction, severe renal impairment (CrCl <30ml/min), mild to moderate hepatic impairment. Contraindications (such as concurrent nitrate use) still apply. Nasal sprays like Spontan deliver PDE5 inhibitors directly through a fine mist that’s absorbed by the nasal mucosa. Larger Absorption Surface:The nasal cavity’s extensive surface area enhances rapid absorption. Optimised pH Levels:Formulated to work best at a pH of 4–7, ensuring effective sildenafil pink pill absorption and swift results.

Sildenafil spray is approved in some regions for ED.
It may provide a more convenient dosing method.
Users should avoid driving until effects are known.
The spray’s rapid absorption may enhance spontaneity.
It is important to monitor blood pressure when using.
Sildenafil spray should not be used with grapefruit juice.
It’s essential to disclose all health conditions to the doctor.
The spray formulation might reduce medication costs.
It can be part of a healthy lifestyle for better results.
Consistent application improves and prolongs effectiveness.
Always consult healthcare providers before starting.

Consistency:By bypassing the gastrointestinal tract, the medication reaches your bloodstream more predictably, leading to a faster and more reliable response. If nasal spray isn’t the right fit or if you’d like to explore other avenues, RHC also offers information on: Intracavernosal Injection Therapy:For men who haven’t achieved the desired results with oral or nasal spray treatments, intracavernosal injection therapy is a viable option. This involves injecting a small dose of ED medication directly into the penis. The method allows for a rapid and robust erection, and it can be particularly effective when other treatments have failed.

Substance/Class	Effect on Sildenafil Spray	Recommendation
Nitrates	Potent hypotensive effect	Avoid concomitant use
Alpha-blockers	Increased risk of low blood pressure	Use with caution, under supervision
Alcohol	Enhances side effects	Limit or avoid consumption
Other PDE5 inhibitors	Increased risk of adverse effects	Do not combine

After receiving proper training from a health care professional, patients can administer these injections at home.

8. Use In Specific Populations

Abnormal penile anatomy or predisposition to priapism (eg, sickle cell anaemia, multiple myeloma or leukaemia). Advise patients to report immediately any sudden changes in vision (and to discontinue treatment if occur) or erection lasting >4 hrs. Common: dizziness, visual colour distortions, visual disturbance, vision blurred, flushing, nasal congestion, nausea, dyspepsia. ● Hezkue® is the first PDE-5 inhibitor suspension spray for erectile dysfunction that offers flexible dose adjustment based on individual patient needs.2 Hezkue® uses a suspension technology that provides fast absorption starting within 5 minutes.2–4● A prospective open-label, single-centre, two-way crossover study evaluated the pharmacokinetics, safety and tolerability of 100mg of sildenafil oromucosal spray (8 pumps) and 100mg sildenafil (Viagra®) tablets in 52 fasted healthy male volunteers.3 ● Initial absorption of sildenafil oromucosal spray was observed within 5 minutes of administration, while sildenafil tablets showed no absorption at that time. The absorption rate (Cmax/time of the maximum plasma concentration [Tmax]) of the oromucosal spray was statistically significantly faster than sildenafil tablets at 5–20 minutes and twice as fast as that of sildenafil tablets 20 minutes after administration (16.00ng/ml/min versus 7.84ng/ml/min, p<0.01).

What side effects can happen with Silfin Oral Spray?

The rate of absorption was not significantly different overall between the oromucosal spray and tablets. In addition, the bioavailability (area under the curve [AUC] ratio) was three times higher for the oromucosal spray than for the tablets 20 minutes after administration (646.92ng/ml/min versus 199.21ng/ml/min, p<0.01).3,4● Sildenafil oromucosal spray delivers the same efficacious doses as sildenafil tablets, with no new safety concerns or oral mucosal safety issues.2,3● In a cross-sectional study, 81 sexually active men with new-onset sexual dysfunction, were treated with sildenafil 50mg orodispersible film for 12 weeks then, after washout, with sildenafil 50mg oral suspension for 12 weeks. At follow-up after each 12-week period, patients completed the International Index of Erectile Function (IIEF), the Patient Global Impression of Improvement (PGI-I) and the Psychological and Interpersonal Relationship Scales-Short Form (PAIRS-SF) questionnaires. Sildenafil oral suspension demonstrated higher satisfaction and spontaneity scores and better overall patient satisfaction when compared with sildenafil orodispersible film (all p<0.01).5● A nationwide Spanish study of 30 urologists and andrologists, aggregating information from the last 6 patients who attended their practice who were treated with Hezkue®, indicated that most patients were highly satisfied with the product due to its formulation, opportunities for flexible dosing, convenience and discreetness.6 Pharmacokinetic parameters of a novel sildenafil oral liquid suspension administered to healthy adult men under fasted conditions. Effectiveness and patient satisfaction with the new sildenafil oral suspension formulation compared to sildenafil oro-dispersible film: a real-life study. It’s important to discuss potential risks, dosing, and technique with your provider to ensure safety and effectiveness.

7. Drug Interactions

That’s an important detail in effective erectile dysfunction treatment.”Man: “No—I took it after dinner with my partner.” After this exchange, I explain how these medications work, their differences, and the correct way to use them—emphasising that details like timing and meal choices are critical to successful ED treatment. Most of us know about the “magic blue pill” and its siblings. These medications are available in various forms: Capsules, tablets, troches, oral strips, and nasal spray delivery. Timing Is Crucial:The devil is in the details when it comes to ED medications—they only work if taken correctly. For example, sildenafil works best on an empty stomach because high-fat meals can delay its absorption, and it typically takes about one hour to start working.

What are the serious side effects of sildenafil?

Similarly, tadalafil lasts longer in the body but also generally requires roughly one hour to reach maximum effect. In contrast, intranasal formulations—such as nasal spray forms of Levitra and oral Avanafil—are designed for a faster onset, usually working within 15 to 30 minutes. These nuances highlight why proper advice and guidance from a health care provider are essential to get the most out of your ED treatment. Personalised Response:Every man’s body responds differently. If one medication gives you a good response with minimal side effects, that might be your best option. Daily Tadalafil:Studies indicate that daily low-dose tadalafil not only helps achieve erections on demand but may also assist young men in regaining spontaneous erectile function over time.

Step	Instruction	Tips
Preparation	Shake the bottle before use	Ensure proper mixing
Positioning	Hold spray 2-3 inches from the tongue/mucosa	Avoid spitting immediately
Administration	Press spray button for 1-2 seconds	Do not swallow immediately
Post-application	Wait 10 minutes before sexual activity	For optimal absorption

For more details on these alternatives, check our related articles here. Q: Who is a good candidate for nasal spray ED medication? A: Nasal spray formulations can be ideal for men looking for a faster onset and those who may experience fewer side effects compared to oral tablets.

Sildenafil spray is a topical form used for erectile dysfunction treatment.
It offers quick absorption due to its spray formulation.
Typically, sildenafil spray acts faster than oral tablets.
The spray is applied under the tongue for rapid effect.
Dosage varies depending on individual health and response.
It is important to follow prescribed instructions for safety.
Sildenafil spray may cause side effects like headache or flushing.
It should not be used with nitrates or certain medications.
Long-term safety data on sildenafil spray is limited.
It is prescribed by a healthcare professional.
Always store sildenafil spray in a cool, dry place.